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Get ultra high purity nitrogen, helium, hydrogen, and argon for liquid chromatography-tandem mass spectrometry.
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Learn more about our liquid chromatography–tandem mass spectrometry gases and the services we offer.
LC-MS/MS is a technique that combines liquid chromatography separation with tandem mass spectrometry detection to identify and quantify compounds in complex samples.
Industrial gases serve as carrier gases, collision gases, and nebulizing gases that enable proper sample ionization, fragmentation, and detection. They must meet ultra high purity standards to prevent contamination and ensure accurate results.
High-purity gases minimize background interference, improve signal-to-noise ratios, and extend instrument life. They also ensure consistent analytical performance and reduce maintenance requirements.
Nitrogen is the main nebulizing gas in electrospray ionization sources that helps convert liquid samples into gas-phase ions for mass spectrometric analysis. It also functions as a drying gas to remove solvent molecules and as a curtain gas to prevent contamination of the ion source.
Helium is used as a collision gas in triple quadrupole mass spectrometers, where it facilitates controlled fragmentation of precursor ions to generate characteristic product ions.
Hydrogen serves as a collision gas alternative to helium and as a carrier gas in some LC-MS/MS configurations. It also works as a fuel gas for flame ionization detectors when LC-MS/MS systems are coupled with additional detection methods.
LC-MS/MS applications typically require ultra high purity gases (99.999% or higher) with extremely low moisture and hydrocarbon content. Specialized gas purification systems may be needed to achieve the stringent purity requirements.
LC-MS/MS is widely used in pharmaceutical development, clinical diagnostics, environmental testing, food safety analysis, and forensic laboratories.
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Supporting manufacturing, preservation, sterilization, and research, ensuring high-quality pharmaceutical production and safety.
Enhance food preservation, packaging, safety, and quality in food processing operations.
Support production, processing, and safety in chemical manufacturing operations.
Fuelling precise analysis, research, and equipment calibration, ensuring accurate and reliable results.
Supporting research, sterilization, analysis, and equipment maintenance, ensuring high standards of safety and efficiency.
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